Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM84238
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
49.2±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84238
Synonyms:
2-(4-chlorophenyl)sulfanyl-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]acetamide | 2-(4-chlorophenyl)sulfanyl-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]ethanamide | 2-[(4-chlorophenyl)sulfanyl]-N-(4-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)acetamide | 2-[(4-chlorophenyl)thio]-N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)acetamide | 2-[(4-chlorophenyl)thio]-N-[4-(2-oxazolo[4,5-b]pyridinyl)phenyl]acetamide | MLS000325420 | SMR000160696 | cid_1016754
Type:
Small organic molecule
Emp. Form.:
C20H14ClN3O2S
Mol. Mass.:
395.862
SMILES:
Clc1ccc(SCC(=O)Nc2ccc(cc2)-c2nc3ncccc3o2)cc1
Structure:
Search PDB for entries with ligand similarity: