Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM84254
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
10100±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84254
Synonyms:
MLS000393695 | N-(4-methyl-3-morpholin-4-ylsulfonyl-phenyl)-4-morpholin-4-yl-3-nitro-benzamide | N-(4-methyl-3-morpholin-4-ylsulfonylphenyl)-4-morpholin-4-yl-3-nitrobenzamide | N-(4-methyl-3-morpholinosulfonyl-phenyl)-4-morpholino-3-nitro-benzamide | N-[4-methyl-3-(4-morpholinylsulfonyl)phenyl]-4-(4-morpholinyl)-3-nitrobenzamide | SMR000241421 | cid_3933628
Type:
Small organic molecule
Emp. Form.:
C22H26N4O7S
Mol. Mass.:
490.529
SMILES:
Cc1ccc(NC(=O)c2ccc(N3CCOCC3)c(c2)[N+]([O-])=O)cc1S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: