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Target
Beta-2 adrenergic receptor
Ligand
BDBM84258
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
1460±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84258
Synonyms:
2-{[5-(azepan-1-ylsulfonyl)-3-methyl-1-benzofuran-2-yl]carbonyl}-1,2,3,4-tetrahydroisoquinoline | MLS000585982 | SMR000207762 | [5-(1-azepanylsulfonyl)-3-methyl-2-benzofuranyl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone | [5-(azepan-1-ylsulfonyl)-3-methyl-1-benzofuran-2-yl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone | [5-(azepan-1-ylsulfonyl)-3-methyl-benzofuran-2-yl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone | cid_4184788
Type:
Small organic molecule
Emp. Form.:
C25H28N2O4S
Mol. Mass.:
452.566
SMILES:
Cc1c(oc2ccc(cc12)S(=O)(=O)N1CCCCCC1)C(=O)N1CCc2ccccc2C1
Structure:
Search PDB for entries with ligand similarity: