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Target
Oxoeicosanoid receptor 1
Ligand
BDBM50446952
Substrate
n/a
Meas. Tech.
ChEBML_1696692
IC50
16±n/a nM
Citation
 Ye, Q; Chourey, S; Wang, R; Chintam, NR; Gravel, S; Powell, WS; Rokach, J Structure-activity relationship study of?-oxidation resistant indole-based 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) receptor antagonists. Bioorg Med Chem Lett 27:4770-4776 (2017) [PubMed]  Article 
Target
Name:
Oxoeicosanoid receptor 1
Synonyms:
5-oxo-ETE G-protein coupled receptor | G-protein coupled receptor 170 | G-protein coupled receptor R527 | G-protein coupled receptor TG1019 | GPR170 | OXER1 | OXER1_HUMAN | Oxoeicosanoid receptor 1 | TG 1019 | TG1019
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45833.20
Organism:
Homo sapiens (Human)
Description:
TG 1019 0 HUMAN::Q8TDS5
Residue:
423
Sequence:
MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
  
Inhibitor
Name:
BDBM50446952
Synonyms:
CHEMBL3115775
Type:
Small organic molecule
Emp. Form.:
C21H28ClNO3
Mol. Mass.:
377.905
SMILES:
CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Structure:
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