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Target
Adenosine receptor A3
Ligand
BDBM50449648
Substrate
n/a
Meas. Tech.
ChEMBL_1740323 (CHEMBL4156073)
Ki
6.4±n/a nM
Citation
 Varano, F; Catarzi, D; Vincenzi, F; Falsini, M; Pasquini, S; Borea, PA; Colotta, V; Varani, K Structure-activity relationship studies and pharmacological characterization of N Eur J Med Chem 155:552-561 (2018) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50449648
Synonyms:
CHEMBL4161758
Type:
Small organic molecule
Emp. Form.:
C14H11N5OS2
Mol. Mass.:
329.4
SMILES:
Nc1nc(NCc2cccs2)nc2sc(nc12)-c1ccco1
Structure:
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