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Target
Alpha-galactosidase
Ligand
BDBM50456586
Substrate
n/a
Meas. Tech.
ChEMBL_1757450 (CHEMBL4192458)
IC50
17000±n/a nM
Citation
 Martínez-Bailén, M; Carmona, AT; Moreno-Clavijo, E; Robina, I; Ide, D; Kato, A; Moreno-Vargas, AJ Tuning of ?-glucosidase and ?-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid molecules. Eur J Med Chem 138:532-542 (2017) [PubMed]  Article 
Target
Name:
Alpha-galactosidase
Synonyms:
α-galactosidase | AGAL_COFAR | Alpha-galactosidase
Type:
Protein
Mol. Mass.:
41306.82
Organism:
Coffea arabica (Coffee beans)
Description:
n/a
Residue:
378
Sequence:
MVKSPGTEDYTRRSLLANGLGLTPPMGWNSWNHFRCNLDEKLIRETADAMVSKGLAALGYKYINLDDCWAELNRDSQGNLVPKGSTFPSGIKALADYVHSKGLKLGIYSDAGTQTCSKTMPGSLGHEEQDAKTFASWGVDYLKYDNCNNNNISPKERYPIMSKALLNSGRSIFFSLCEWGEEDPATWAKEVGNSWRTTGDIDDSWSSMTSRADMNDKWASYAGPGGWNDPDMLEVGNGGMTTTEYRSHFSIWALAKAPLLIGCDIRSMDGATFQLLSNAEVIAVNQDKLGVQGNKVKTYGDLEVWAGPLSGKRVAVALWNRGSSTATITAYWSDVGLPSTAVVNARDLWAHSTEKSVKGQISAAVDAHDSKMYVLTPQ
  
Inhibitor
Name:
BDBM50456586
Synonyms:
CHEMBL4205735
Type:
Small organic molecule
Emp. Form.:
C18H20N4O3
Mol. Mass.:
340.3764
SMILES:
COc1ccc2cc(ccc2c1)-c1cn(C[C@H]2NC[C@@H](O)[C@H]2O)nn1 |r|
Structure:
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