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Target14-3-3 protein zeta/delta
LigandBDBM50102295
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1772678
IC50 9300±n/a nM
Citation Stevers, LMSijbesma, EBotta, MMacKintosh, CObsil, TLandrieu, ICau, YWilson, AJKarawajczyk, AEickhoff, JDavis, JHann, MO'Mahony, GDoveston, RGBrunsveld, LOttmann, C Modulators of 14-3-3 Protein-Protein Interactions. J Med Chem61:3755-3778 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
14-3-3 protein zeta/delta
Name:14-3-3 protein zeta/delta
Synonyms:14-3-3 protein zeta/delta | KCIP-1 | Protein kinase C inhibitor protein 1 | YWHAZ
Type:PROTEIN
Mol. Mass.:27731.18
Organism:Homo sapiens
Description:ChEMBL_117504
Residue:245
Sequence:
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR
VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK
MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG
EGGEN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50102295
NameBDBM50102295
Synonyms:4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethyl-pyridin-2-ylazo)-benzoic acid | CHEMBL119235
TypeSmall organic molecule
Emp. Form.C15H14N3O8P
Mol. Mass.395.2607
SMILESCc1nc(N=Nc2ccc(cc2)C(O)=O)c(COP(O)(O)=O)c(C=O)c1O |w:5.5|
Structure
n/a