Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50464762
Substrate
n/a
Meas. Tech.
ChEMBL_1782292 (CHEMBL4253809)
Ki
>10000±n/a nM
Citation
 Duroux, R; Agouridas, L; Renault, N; El Bakali, J; Furman, C; Melnyk, P; Yous, S Antagonists of the adenosine A Eur J Med Chem 144:151-163 (2018) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50464762
Synonyms:
CHEMBL4289393
Type:
Small organic molecule
Emp. Form.:
C32H34N4O6
Mol. Mass.:
570.6356
SMILES:
CCOCCOc1ccc(cc1)N1CCN(CCC(=O)Nc2cc(-c3ccco3)c3oc(nc3c2)-c2ccco2)CC1
Structure:
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