Reaction Details Report a problem with these data
Target
Thiosulfate sulfurtransferase
Ligand
BDBM50350465
Substrate
n/a
Meas. Tech.
ChEMBL_1797977 (CHEMBL4270094)
IC50
>100000±n/a nM
Citation
 Kunkle, T; Abdeen, S; Salim, N; Ray, AM; Stevens, M; Ambrose, AJ; Victorino, J; Park, Y; Hoang, QQ; Chapman, E; Johnson, SM Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. J Med Chem 61:10651-10664 (2018) [PubMed]  Article 
Target
Name:
Thiosulfate sulfurtransferase
Synonyms:
2.8.1.1 | Rhodanese | THTR_HUMAN | TST | Thiosulfate sulfurtransferase
Type:
PROTEIN
Mol. Mass.:
33432.06
Organism:
Homo sapiens
Description:
ChEMBL_118080
Residue:
297
Sequence:
MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFDIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLVDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDLSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
  
Inhibitor
Name:
BDBM50350465
Synonyms:
AMPICILLIN | AY-6108 | Amcill | Aminobenzylpenicillin | Ampicillin sulfate
Type:
Small organic molecule
Emp. Form.:
C16H19N3O4S
Mol. Mass.:
349.405
SMILES:
CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O |r|
Structure:
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