Reaction Details Report a problem with these data
Target
Phospholipase A1 member A
Ligand
BDBM50031282
Substrate
n/a
Meas. Tech.
ChEMBL_155873 (CHEMBL769592)
IC50
80400±n/a nM
Citation
 Kotretsou, S; Mingeot-Leclercq, MP; Constantinou-Kokotou, V; Brasseur, R; Georgiadis, MP; Tulkens, PM Synthesis and antimicrobial and toxicological studies of amino acid and peptide derivatives of kanamycin A and netilmicin. J Med Chem 38:4710-9 (1995) [PubMed]  Article 
Target
Name:
Phospholipase A1 member A
Synonyms:
3.1.1.- | PLA1A_RAT | PS-PLA1 | Phosphatidylserine-specific phospholipase A1 | Phospholipase A1 member A | Pla1a | Pspla1
Type:
PROTEIN
Mol. Mass.:
50213.12
Organism:
Rattus norvegicus
Description:
ChEMBL_12251
Residue:
456
Sequence:
MCPGLWGTCFWLWGSLLWLSIGRSGNVPPTTQPKCTDFQSANLLRGTNLKVQFLLFTPSDPGCGQLVEEDSDIRNSEFNASLGTKLIIHGFRALGTKPSWINKFIRALLRAADANVIAVDWVYGSTGMYFSAVENVVKLSLEISRFLSKLLELGVSESSIHIIGVSLGAHVGGMVGHFYKGQLGRITGLDPAGPEYTRASLEERLDSGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPAFIHAGYSYLICDHMRAVHLYISALENTCPLMAFPCASYKAFLAGDCLDCFNPFLLSCPRIGLVERGGVKIEPLPKEVRVYLQTTSSAPYCVHHSLVEFNLKEKRKKDTSIEVTFLGNNVTSSVKITIPKDHLEGRGIIAHQNPHCQINQVKLKFHISSRVWRKDRTPIVGTFCTAPLPVNDSKKTVCIPEPVRLQVSMAVLRDLKMACV
  
Inhibitor
Name:
BDBM50031282
Synonyms:
CHEBI:17630 | Kanamycin
Type:
Small organic molecule
Emp. Form.:
C18H36N4O11
Mol. Mass.:
484.4986
SMILES:
NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: