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Target
Catechol O-methyltransferase
Ligand
BDBM50028546
Substrate
n/a
Meas. Tech.
ChEBML_47077
Ki
7260000±n/a nM
Citation
 Borchardt, RT; Bhatia, P Catechol O-methyltransferase. 12. Affinity labeling the active site with the oxidation products of 5,6-dihydroxyindole. J Med Chem 25:263-71 (1982) [PubMed]  Article 
Target
Name:
Catechol O-methyltransferase
Synonyms:
COMT_RAT | Catechol O-methyltransferase | Catechol-O-methyltransferase | Comt
Type:
Enzyme
Mol. Mass.:
29594.09
Organism:
Rattus norvegicus (Rat)
Description:
n/a
Residue:
264
Sequence:
MPLAAVSLGLLLLALLLLLRHLGWGLVTIFWFEYVLQPVHNLIMGDTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGPSSPDKS
  
Inhibitor
Name:
BDBM50028546
Synonyms:
4,7-Dimethyl-1H-indole-5,6-diol | CHEMBL90203
Type:
Small organic molecule
Emp. Form.:
C10H11NO2
Mol. Mass.:
177.1998
SMILES:
Cc1c(O)c(O)c(C)c2[nH]ccc12
Structure:
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