Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 8
Ligand
BDBM50344959
Substrate
n/a
Meas. Tech.
ChEMBL_836315 (CHEMBL2076479)
Ki
35600±n/a nM
Citation
 Nagata, Y; Kusuhara, H; Endou, H; Sugiyama, Y Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus. Mol Pharmacol 61:982-8 (2002) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 8
Synonyms:
Oat3 | Organic anion transporter 3 | S22A8_RAT | Slc22a8 | rOat3
Type:
PROTEIN
Mol. Mass.:
59199.83
Organism:
Rattus norvegicus
Description:
ChEMBL_1482580
Residue:
536
Sequence:
MTFSEILDRVGSMGPFQYLHVTLLALPVLGIANHNLLQIFTATTPVHHCRPPPNASIGPWVLPLDPNGKPEKCLRFVHLPNASLPNDTQRATEPCLDGWIYNSTRDTIVIEWDLVCSSNKLKEMAQSIFMAGILVGGPVIGELSDRFGRKPILTWSYLMLAASGSGAAFSPSLPVYMIFRFLCGCSISGISLSTVILNVEWVPTSMRAISSTSIGYCYTIGQFILSGLAYAIPQWRWLQLTSSAPFFIFSLLSWWVPESIRWLVLSGKYSKALKTLQRVATFNGKKEEGKKLTIEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFSTGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSLSYLGRRITQSFLLLLAGGAILALIFVPSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNVWARVGSMIAPLVKITGELQPFIPNVIFGTTALLGGSAAFFLLETLNRPLPETIEDIQNWHKQVQKTKQESEAEKASQIIPLKTGG
  
Inhibitor
Name:
BDBM50344959
Synonyms:
17beta-Estradiol-17-(beta-D-glucuronide) | CHEMBL1697724 | E17β-glucuronide | estradiol 17b glucuronide
Type:
Small organic molecule
Emp. Form.:
C24H32O8
Mol. Mass.:
448.5061
SMILES:
C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O |r|
Structure:
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