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TargetSolute carrier family 22 member 8
LigandBDBM50370587
Substrate/Competitorn/a
Meas. Tech.ChEMBL_838483
Ki 780000±n/a nM
Citation Jung, KYTakeda, MShimoda, MNarikawa, STojo, AKim, DKChairoungdua, AChoi, BKKusuhara, HSugiyama, YSekine, TEndou, H Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity: in comparison with rOAT1. Life Sci70:1861-74 (2002) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Solute carrier family 22 member 8
Name:Solute carrier family 22 member 8
Synonyms:Oat3 | Organic anion transporter 3 | Slc22a8 | rOat3
Type:PROTEIN
Mol. Mass.:59199.83
Organism:Rattus norvegicus
Description:ChEMBL_1482580
Residue:536
Sequence:
MTFSEILDRVGSMGPFQYLHVTLLALPVLGIANHNLLQIFTATTPVHHCRPPPNASIGPW
VLPLDPNGKPEKCLRFVHLPNASLPNDTQRATEPCLDGWIYNSTRDTIVIEWDLVCSSNK
LKEMAQSIFMAGILVGGPVIGELSDRFGRKPILTWSYLMLAASGSGAAFSPSLPVYMIFR
FLCGCSISGISLSTVILNVEWVPTSMRAISSTSIGYCYTIGQFILSGLAYAIPQWRWLQL
TSSAPFFIFSLLSWWVPESIRWLVLSGKYSKALKTLQRVATFNGKKEEGKKLTIEELKFN
LQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFSTGFAYYSLAMGVEEFGVNIYILQI
IFGGVDIPAKFITILSLSYLGRRITQSFLLLLAGGAILALIFVPSEMQLLRTALAVFGKG
CLSGSFSCLFLYTSELYPTVLRQTGMGISNVWARVGSMIAPLVKITGELQPFIPNVIFGT
TALLGGSAAFFLLETLNRPLPETIEDIQNWHKQVQKTKQESEAEKASQIIPLKTGG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50370587
NameBDBM50370587
Synonyms:CEFAZOLIN
TypeSmall organic molecule
Emp. Form.C14H14N8O4S3
Mol. Mass.454.507
SMILESCc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn2cnnn2)C3=O)C(O)=O)s1 |r,t:7|
Structure
n/a