Reaction Details Report a problem with these data
Target
Solute carrier family 15 member 1
Ligand
BDBM50370586
Substrate
n/a
Meas. Tech.
ChEMBL_837978 (CHEMBL2075147)
Ki
710000±n/a nM
Citation
 Ganapathy, ME; Prasad, PD; Mackenzie, B; Ganapathy, V; Leibach, FH Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2. Biochim Biophys Acta 1324:296-308 (1997) [PubMed]  Article 
Target
Name:
Solute carrier family 15 member 1
Synonyms:
Intestinal H(+)/peptide cotransporter | Oligopeptide transporter small intestine isoform | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | S15A1_HUMAN | SLC15A1
Type:
PROTEIN
Mol. Mass.:
78818.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1488839
Residue:
708
Sequence:
MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGPMSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
  
Inhibitor
Name:
BDBM50370586
Synonyms:
7-(2-(2-amino-4-thiazolyl)-4-carboxy-2-butenoylamino)-3-cephem-4-carboxylic acid | 7432-S | CEFTIBUTEN | Cedax | Cedex | SCH-39720
Type:
Small organic molecule
Emp. Form.:
C15H14N4O6S2
Mol. Mass.:
410.425
SMILES:
Nc1nc(cs1)C(=C\CC(O)=O)\C(=O)N[C@H]1[C@H]2SCC=C(N2C1=O)C(O)=O |r,c:20|
Structure:
Search PDB for entries with ligand similarity: