Reaction Details Report a problem with these data
Target
Acetolactate synthase, chloroplastic
Ligand
BDBM50487034
Substrate
n/a
Meas. Tech.
ChEMBL_906554 (CHEMBL3067256)
Ki
790000±n/a nM
Citation
 Li, YX; Luo, YP; Xi, Z; Niu, C; He, YZ; Yang, GF Design and syntheses of novel phthalazin-1(2H)-one derivatives as acetohydroxyacid synthase inhibitors. J Agric Food Chem 54:9135-9 (2006) [PubMed]  Article 
Target
Name:
Acetolactate synthase, chloroplastic
Synonyms:
AHAS | ALS | Acetolactate synthase | CSR1 | ILVB_ARATH | TZP5
Type:
PROTEIN
Mol. Mass.:
72585.19
Organism:
Arabidopsis thaliana
Description:
ChEMBL_934103
Residue:
670
Sequence:
MAAATTTTTTSSSISFSTKPSPSSSKSPLPISRFSLPFSLNPNKSSSSSRRRGIKSSSPSSISAVLNTTTNVTTTPSPTKPTKPETFISRFAPDQPRKGADILVEALERQGVETVFAYPGGASMEIHQALTRSSSIRNVLPRHEQGGVFAAEGYARSSGKPGICIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRIIEEAFFLATSGRPGPVLVDVPKDIQQQLAIPNWEQAMRLPGYMSRMPKPPEDSHLEQIVRLISESKKPVLYVGGGCLNSSDELGRFVELTGIPVASTLMGLGSYPCDDELSLHMLGMHGTVYANYAVEHSDLLLAFGVRFDDRVTGKLEAFASRAKIVHIDIDSAEIGKNKTPHVSVCGDVKLALQGMNKVLENRAEELKLDFGVWRNELNVQKQKFPLSFKTFGEAIPPQYAIKVLDELTDGKAIISTGVGQHQMWAAQFYNYKKPRQWLSSGGLGAMGFGLPAAIGASVANPDAIVVDIDGDGSFIMNVQELATIRVENLPVKVLLLNNQHLGMVMQWEDRFYKANRAHTFLGDPAQEDEIFPNMLLFAAACGIPAARVTKKADLREAIQTMLDTPGPYLLDVICPHQEHVLPMIPSGGTFNDVITEGDGRIKY
  
Inhibitor
Name:
BDBM50487034
Synonyms:
CHEMBL2253254
Type:
Small organic molecule
Emp. Form.:
C15H14N4O4
Mol. Mass.:
314.2961
SMILES:
COc1cc(OC)nc(Oc2cccc3c(C)n[nH]c(=O)c23)n1
Structure:
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