Reaction Details
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Peroxisome proliferator-activated receptor alpha
Ligand
BDBM50240347
Substrate
n/a
Meas. Tech.
ChEMBL_909356 (CHEMBL3055183)
IC50
1200±n/a nM
Citation
TBA Med Chem Res 18:8-19 (2009) Article More Info.:
Target
Name:
Peroxisome proliferator-activated receptor alpha
Synonyms:
NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha)
Type:
Enzyme
Mol. Mass.:
52222.08
Organism:
Homo sapiens (Human)
Description:
Q07869
Residue:
468
Sequence:
MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
Inhibitor
Name:
BDBM50240347
Synonyms:
(9,12,15)-linolenic acid | (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid | (Z,Z,Z)-9,12,15-octadecatrienoic acid | 9-cis,12-cis,15-cis-octadecatrienoic acid | ALA | CHEMBL8739 | all-cis-9,12,15-octadecatrienoic acid | alpha-linolenic acid | cid_5280934 | cis,cis,cis-9,12,15-octadecatrienoic acid | cis-Delta(9,12,15)-octadecatrienoic acid | linolenic acid
Type:
Small organic molecule
Emp. Form.:
C18H30O2
Mol. Mass.:
278.4296
SMILES:
CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O
Structure:
