Reaction Details Report a problem with these data
Target
Dipeptidyl peptidase 3
Ligand
BDBM25758
Substrate
n/a
Meas. Tech.
ChEMBL_913308 (CHEMBL3053565)
IC50
360000±n/a nM
Citation
 Dhanda, S; Singh, J; Singh, H Goat brain enkephalin degrading enzyme: interaction with analgesic and antihypertensive drugs Med Chem Res 20:1294-7 (2011)    Article 
Target
Name:
Dipeptidyl peptidase 3
Synonyms:
3.4.14.4 | Dipeptidyl aminopeptidase III | Dipeptidyl peptidase 3 | Dipeptidyl peptidase III | M91_14005
Type:
PROTEIN
Mol. Mass.:
82027.05
Organism:
Bos mutus
Description:
ChEMBL_117383
Residue:
730
Sequence:
MADTQYILPNDIGVSSLDCREAFRLLSSTERLYAHYLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQICGELMFSLESRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVGQDGKPSYEVRLASVLGTEPNLDSEMNSKLKSYEFQGSHFRVTRGDYAPILQKVVEQLEKAKAYAANSHQEQMLAQYIESFTQGSIEAHKKGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFEWLVASAEQLLKELPWPPAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFMQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPRVLEIFGFEGADAEDVVYVNWLNMVRAGLLALEFYTPEASSWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVRLDRDKIRTVGKPALERFLRRLQVLKSTGDVAGGRALYEGYAAVTDAPPECFLSLRDTVLLRKEARKLIVQPNTRLEGSEVQLLEYEASAAGLIRSFSERFLEDGPELEKILTQLATADAQCWKGPQ
  
Inhibitor
Name:
BDBM25758
Synonyms:
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide | Albetol | Labetolol | Normodyne | labetalol
Type:
Small organic molecule
Emp. Form.:
C19H24N2O3
Mol. Mass.:
328.4055
SMILES:
CC(CCc1ccccc1)NCC(O)c1ccc(O)c(c1)C(N)=O
Structure:
Search PDB for entries with ligand similarity: