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Target
Nicotinic acetylcholine receptor alpha 5 subunit
Ligand
BDBM50212288
Substrate
n/a
Meas. Tech.
ChEMBL_916315 (CHEMBL3081642)
IC50
20±n/a nM
Citation
 Kagabu, S; Kiriyama, K; Nishiwaki, H; Kumamoto, Y; Tada, T; Nishimura, K Asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine: preparation, resolution and biological activities toward insects and their nerve preparations. Biosci Biotechnol Biochem 67:980-8 (2003) [PubMed]  Article 
Target
Name:
Nicotinic acetylcholine receptor alpha 5 subunit
Synonyms:
Nicotinic acetylcholine receptor alpha 5 subunit | nAChRalpha5
Type:
PROTEIN
Mol. Mass.:
88489.00
Organism:
Musca domestica
Description:
ChEMBL_106552
Residue:
781
Sequence:
MMWEMLILWAVHLSLTAIATLYANVRTALSQTAQQIVRAVIAATTLPIIQRIQQQQHETEKQQQQLQHGKHVEDIHLPAAGARYASASSSRLPPSSADATIWPRAPPELPQTEKLSSAPPPPSSSSTLLMQTKPAHKKPVHGRNFPPQQKNRMQPVSHLQYQQQQQQQLSLPSPAEPQPQHYKQQQQQQGQERLGQQVNINNITSSSNGGNTCSSNSFTATTSIAATTTTSILTLWQHCHRRYRPHQLLPLLTTKGLNKYSWIFLLIYLNLSAKVCLAGYNEKRLLHDLLDTYNTLERPVLNESDPLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGIKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDETGGDISSYVLNGEWELLGVPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEMSEWIRVVFLCWLPWILRMHRPGRPIIMDFTSTPCSDTSSERKHQILSDVELKERSSKSLLANVLDIDDDFRNVRPMTPGGTLPHNPAFYRTVYGYLENLQGDDGSIGPIGSTRMPDAVTHHTCIKTQTEYELSLILKEIRFITDQLRKEDEENGIANDWKFAAMVVDRLCLIIFTMFAILATIAVLLSAPHVIVS
  
Inhibitor
Name:
BDBM50212288
Synonyms:
(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine | (E)-imidacloprid | CHEMBL406819
Type:
Small organic molecule
Emp. Form.:
C9H10ClN5O2
Mol. Mass.:
255.661
SMILES:
[O-][N+](=O)NC1=NCCN1Cc1ccc(Cl)nc1 |t:4|
Structure:
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