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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50242349
Substrate
n/a
Meas. Tech.
ChEMBL_933250 (CHEMBL3069174)
IC50
1600±n/a nM
Citation
  TBA Med Chem Res 22:3126-3133 (2013)    Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50242349
Synonyms:
(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic acid | (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid | (all-Z)-5,8,11,14,17-eicosapentaenoic acid | 5,8,11,14,17-EICOSAPENTAENOIC ACID | 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid | CHEMBL460026 | EPA | ICOSAPENT ETHYL | Icosapent | Timnodonic acid | all-cis-icosa-5,8,11,14,17-pentaenoic acid | cis-5,8,11,14,17-eicosapentaenoic acid | cis-Delta(5,8,11,14,17)-eicosapentaenoic acid | omega-3-Eicosapentaenoic Acid | vascepa
Type:
Small organic molecule
Emp. Form.:
C20H30O2
Mol. Mass.:
302.451
SMILES:
CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
Structure:
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