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Target
Metallo-beta-lactamase IMP-1
Ligand
BDBM50493096
Substrate
n/a
Meas. Tech.
ChEMBL_978383 (CHEMBL2424346)
IC50
25600±n/a nM
Citation
 Hiraiwa, Y; Morinaka, A; Fukushima, T; Kudo, T Metallo-?-lactamase inhibitory activity of 3-alkyloxy and 3-amino phthalic acid derivatives and their combination effect with carbapenem. Bioorg Med Chem 21:5841-50 (2013) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase IMP-1
Synonyms:
Metallo beta-lactamase | Metallo-beta-lactamase IMP-1 | blaIMP-1
Type:
PROTEIN
Mol. Mass.:
14898.12
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_116913
Residue:
133
Sequence:
YVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLP
  
Inhibitor
Name:
BDBM50493096
Synonyms:
CHEMBL2420947
Type:
Small organic molecule
Emp. Form.:
C15H19NO5
Mol. Mass.:
293.3151
SMILES:
OCCC1CCN(CC1)c1cccc(C(O)=O)c1C(O)=O
Structure:
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