Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50039472
Substrate
n/a
Meas. Tech.
ChEMBL_99656 (CHEMBL704422)
IC50
4.5±n/a nM
Citation
 Harper, RW; Jackson, WT; Froelich, LL; Boyd, RJ; Aldridge, TE; Herron, DK Leukotriene B4 (LTB4) receptor antagonists: a series of (hydroxyphenyl)pyrazoles. J Med Chem 37:2411-20 (1994) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50039472
Synonyms:
7-{3-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-phenoxy]-propoxy}-8-propyl-chroman-2-carboxylic acid | CHEMBL81401
Type:
Small organic molecule
Emp. Form.:
C27H32N2O6
Mol. Mass.:
480.5528
SMILES:
CCCc1c(OCCCOc2cc(O)c(cc2CC)-c2cc[nH]n2)ccc2CCC(Oc12)C(O)=O
Structure:
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