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Target
D(2) dopamine receptor
Ligand
BDBM50040079
Substrate
n/a
Meas. Tech.
ChEBML_62557
Ki
0.019000±n/a nM
Citation
 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT. J Med Chem 36:221-8 (1993) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50040079
Synonyms:
CHEMBL308524 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-5,6-dimethoxy-benzamide (ioxipride) | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-5,6-dimethoxy-benzamide( NCQ 298)
Type:
Small organic molecule
Emp. Form.:
C16H23IN2O4
Mol. Mass.:
434.2693
SMILES:
CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)cc(OC)c1OC
Structure:
Search PDB for entries with ligand similarity: