Reaction Details Report a problem with these data
Target
Acyl-protein thioesterase 1
Ligand
BDBM50496627
Substrate
n/a
Meas. Tech.
ChEMBL_1300906 (CHEMBL3135193)
Ki
990±n/a nM
Citation
 Davda, D; Martin, BR Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation. Medchemcomm 5:268-276 (2014) [PubMed]  Article 
Target
Name:
Acyl-protein thioesterase 1
Synonyms:
APT-1 | APT1 | Acyl-protein thioesterase 1 (APT1 WT) | LPL-I | LPL1 | LYPA1_HUMAN | LYPLA1 | LysoPLA I | Lysophospholipase 1 | Lysophospholipase I | hAPT1
Type:
Protein
Mol. Mass.:
24670.33
Organism:
Homo sapiens (Human)
Description:
O75608
Residue:
230
Sequence:
MCGNNMSTPLPAIVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSSHIKYICPHAPVRPVTLNMNVAMPSWFDIIGLSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFPQGPIGGANRDISILQCHGDCDPLVPLMFGSLTVEKLKTLVNPANVTFKTYEGMMHSSCQQEMMDVKQFIDKLLPPID
  
Inhibitor
Name:
BDBM50496627
Synonyms:
CHEMBL3133032
Type:
Small organic molecule
Emp. Form.:
C34H42B2N2O3
Mol. Mass.:
548.331
SMILES:
CN(C)CCOB(c1ccccc1)c1ccc(COCc2ccc(cc2)B(OCCN(C)C)c2ccccc2)cc1
Structure:
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