Target
Mu-type opioid receptor
Ligand
BDBM50045779
Substrate
n/a
Meas. Tech.
ChEBML_220391
Ki
0.290000±n/a nM
Citation
 Mitch, CHLeander, JDMendelsohn, LGShaw, WNWong, DTCantrell, BEJohnson, BGReel, JKSnoddy, JDTakemori, AE 3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity. J Med Chem 36:2842-50 (1993) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50045779
Synonyms:
3-[3,4-Dimethyl-1-(4-methyl-pentyl)-piperidin-4-yl]-phenol | CHEMBL97223
Type:
Small organic molecule
Emp. Form.:
C19H31NO
Mol. Mass.:
289.4555
SMILES:
CC(C)CCCN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1
Structure:
Search PDB for entries with ligand similarity: