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Target
Actin, alpha skeletal muscle
Ligand
BDBM50508924
Substrate
n/a
Meas. Tech.
ChEMBL_1835666 (CHEMBL4335799)
IC50
15210±n/a nM
Citation
 Wang, S; Gegenfurtner, FA; Crevenna, AH; Ziegenhain, C; Kliesmete, Z; Enard, W; Müller, R; Vollmar, AM; Schneider, S; Zahler, S Chivosazole A Modulates Protein-Protein Interactions of Actin. J Nat Prod 82:1961-1970 (2019) [PubMed]  Article 
Target
Name:
Actin, alpha skeletal muscle
Synonyms:
ACTA | ACTA1 | ACTS_RABIT | Actin, alpha skeletal muscle | Actin, alpha skeletal muscle, intermediate form | Alpha-actin-1
Type:
PROTEIN
Mol. Mass.:
42042.02
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_119010
Residue:
377
Sequence:
MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF
  
Inhibitor
Name:
BDBM50508924
Synonyms:
CHEMBL4522174
Type:
Small organic molecule
Emp. Form.:
C49H71NO12
Mol. Mass.:
866.0875
SMILES:
[H][C@@]1(O[C@H]2\C=C/C=C/c3coc(n3)[C@H](C)[C@@H](C[C@@H](O)\C=C\C=C\C=C/[C@H](C)[C@]([H])(OC(=O)\C=C/C=C/C=C\C(\C)=C\[C@H]2C)[C@@H](C)[C@@H](O)C[C@@H](C)O)OC)O[C@H](C)[C@@H](O)[C@H](OC)[C@H]1OC |r,c:4,24,33,37,t:6,20,22,35,40|
Structure:
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