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Target
Chitinase
Ligand
BDBM50514508
Substrate
n/a
Meas. Tech.
ChEMBL_1856955 (CHEMBL4357684)
Ki
390±n/a nM
Citation
 Jiang, X; Kumar, A; Motomura, Y; Liu, T; Zhou, Y; Moro, K; Zhang, KYJ; Yang, Q A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors. J Med Chem 63:987-1001 (2020) [PubMed]  Article 
Target
Name:
Chitinase
Synonyms:
Chitinase | OfChi-h
Type:
PROTEIN
Mol. Mass.:
60999.67
Organism:
Ostrinia furnacalis
Description:
ChEMBL_119063
Residue:
553
Sequence:
MGRLAIVVVATLALAAAAPPGKPSLGWGERTFAIVEVNQAATAYNQLVTKRDSADVSVTWNVWSGDPADKARVLLNDKEFWSGTGGAAGSASFKVKKGGRYQMVVELCNADGCSQSDATEIIVADTDGSHLPPLDYNMGEKNKPFKQTSGKVVGAYFVEWGVYPRKFPVDRVPIPNLTHLLYGFIPICGGDGINDSLKEIEGSFQALQRSCSGREDFKVSIHDPWAALQKPQKGLSSWNEPYKGNFGQLMMLKQAKPDLKILPSIGGWTLADPFFFFTDETKRRRFVASVKDFLQTWKFFDGVDIDWEFPGGKGANPNLGSPKDGEIYVLLMKELREMLNELSAETGRKYELTSAISAGWDKIQVVDYSAAQKYMDHIFFMSYDFKGAWSNDTLGHQASLYAPDWNEKETYTTDFGVQFLLAQGVSPKKIVVGVAMYGRGWTGVHGYKDNNPFTGNATGPVKGTWQDGVVDYREIATEIAQGKWEYHYDKVAQAPYVFRPATGDLITYDDARSTIEKGKYVRANKLGGLFAWEIDADNGDILNAMNMGLGNSA
  
Inhibitor
Name:
BDBM50514508
Synonyms:
CHEMBL4549449
Type:
Small organic molecule
Emp. Form.:
C27H23N5O2
Mol. Mass.:
449.5038
SMILES:
CC(NC(=O)c1cc2c(nc3ccccn3c2=O)n(Cc2ccccc2)c1=N)c1ccccc1
Structure:
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