Reaction Details Report a problem with these data
Target
Tyrosinase
Ligand
BDBM50205807
Substrate
n/a
Meas. Tech.
ChEMBL_1908914 (CHEMBL4411360)
Ki
350±n/a nM
Citation
 Pillaiyar, T; Namasivayam, V; Manickam, M; Jung, SH Inhibitors of Melanogenesis: An Updated Review. J Med Chem 61:7395-7418 (2018) [PubMed]  Article 
Target
Name:
Tyrosinase
Synonyms:
LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB
Type:
Protein
Mol. Mass.:
60388.08
Organism:
Homo sapiens (Human)
Description:
P14679
Residue:
529
Sequence:
MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLGAAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
  
Inhibitor
Name:
BDBM50205807
Synonyms:
CHEMBL3978212
Type:
Small organic molecule
Emp. Form.:
C14H9NO5
Mol. Mass.:
271.225
SMILES:
Oc1ccc2C(=O)\C(Oc2c1)=C\c1ccc(=O)n(O)c1
Structure:
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