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Target
Adenosine kinase
Ligand
BDBM50375654
Substrate
n/a
Meas. Tech.
ChEMBL_1927381 (CHEMBL4430453)
Ki
16±n/a nM
Citation
 Köse, M; Schiedel, AC; Bauer, AA; Poschenrieder, H; Burbiel, JC; Akkinepally, RR; Stachel, HD; Müller, CE Focused screening to identify new adenosine kinase inhibitors. Bioorg Med Chem 24:5127-5133 (2016) [PubMed]  Article 
Target
Name:
Adenosine kinase
Synonyms:
ADK | ADK_HUMAN
Type:
PROTEIN
Mol. Mass.:
40545.97
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1467841
Residue:
362
Sequence:
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH
  
Inhibitor
Name:
BDBM50375654
Synonyms:
CHEMBL99203 | US11633415, Compound 5-iodotubercidin
Type:
Small organic molecule
Emp. Form.:
C11H13IN4O4
Mol. Mass.:
392.1498
SMILES:
Nc1ncnc2n(cc(I)c12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r|
Structure:
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