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Target
X-box-binding protein 1
Ligand
BDBM50535815
Substrate
n/a
Meas. Tech.
ChEMBL_1931939 (CHEMBL4477591)
EC50
13±n/a nM
Citation
Xie, M; Zhang, HJ; Deng, AJ; Wu, LQ; Zhang, ZH; Li, ZH; Wang, WJ; Qin, HL Synthesis and Structure-Activity Relationships of N-Dihydrocoptisine-8-ylidene Aromatic Amines and N-Dihydrocoptisine-8-ylidene Aliphatic Amides as Antiulcerative Colitis Agents Targeting XBP1. J Nat Prod 79:775-83 (2016) [PubMed] Article
More Info.:
Target
Name:
X-box-binding protein 1
Synonyms:
Hepatocarcinogenesis-related transcription factor | Htf | X-box-binding protein 1 | X-box-binding protein 1, cytoplasmic form | X-box-binding protein 1, luminal form | XBP1_RAT | Xbp1
Type:
PROTEIN
Mol. Mass.:
29677.58
Organism:
Rattus norvegicus
Description:
ChEMBL_109918
Residue:
267
Sequence:
MVVVAAAPSAASAAPKVLLLSGQPASGGRALPLMVPGPRAAGSEASGTPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLQLENQLLREKTHGLVIENQELRTRLGMNALVTEEVSEAESKGNGVRLVAGSAESAALRLRAPLQQVQAQLSPPQNIFPWILTLLPLQILSLISFWAFWTSWTLSCFSNVLPQSLLIWRNSQRSTQKDLVPYQPPFLCQWGPHQPSWKPLMNSFVLTMYTPSL