Reaction Details Report a problem with these data
Target
P2X purinoceptor 2
Ligand
BDBM50102304
Substrate
n/a
Meas. Tech.
ChEMBL_147550 (CHEMBL754947)
IC50
1200±n/a nM
Citation
 Kim, YC; Brown, SG; Harden, TK; Boyer, JL; Dubyak, G; King, BF; Burnstock, G; Jacobson, KA Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors. J Med Chem 44:340-9 (2001) [PubMed]  Article 
Target
Name:
P2X purinoceptor 2
Synonyms:
ATP receptor | P2RX2_RAT | P2X purinoceptor 2 | P2X2 | P2X2/P2X3 receptor | P2rx2 | Purinergic receptor | Purinergic, P2X2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52625.55
Organism:
RAT
Description:
Purinergic, P2X2 0 RAT::P49653
Residue:
472
Sequence:
MVRRLARGCWSAFWDYETPKVIVVRNRRLGFVHRMVQLLILLYFVWYVFIVQKSYQDSETGPESSIITKVKGITMSEDKVWDVEEYVKPPEGGSVVSIITRIEVTPSQTLGTCPESMRVHSSTCHSDDDCIAGQLDMQGNGIRTGHCVPYYHGDSKTCEVSAWCPVEDGTSDNHFLGKMAPNFTILIKNSIHYPKFKFSKGNIASQKSDYLKHCTFDQDSDPYCPIFRLGFIVEKAGENFTELAHKGGVIGVIINWNCDLDLSESECNPKYSFRRLDPKYDPASSGYNFRFAKYYKINGTTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSIGVGSFLCDWILLTFMNKNKLYSHKKFDKVRTPKHPSSRWPVTLALVLGQIPPPPSHYSQDQPPSPPSGEGPTLGEGAELPLAVQSPRPCSISALTEQVVDTLGQHMGQRPPVPEPSQQDSTSTDPKGLAQL
  
Inhibitor
Name:
BDBM50102304
Synonyms:
CHEMBL116926 | Phosphoric acid mono-(4-formyl-5-hydroxy-6-methyl-2-phenylazo-pyridin-3-ylmethyl) ester
Type:
Small organic molecule
Emp. Form.:
C14H14N3O6P
Mol. Mass.:
351.2512
SMILES:
Cc1nc(N=Nc2ccccc2)c(COP(O)(O)=O)c(C=O)c1O |w:5.5|
Structure:
Search PDB for entries with ligand similarity: