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TargetStromelysin-1
LigandBDBM50056900
Substrate/Competitorn/a
Meas. Tech.ChEMBL_205633
Kd>25000000±n/a nM
Citation Hajduk, PJShuker, SBNettesheim, DGCraig, RAugeri, DJBetebenner, DAlbert, DHGuo, YMeadows, RPXu, LMichaelides, MDavidsen, SKFesik, SW NMR-based modification of matrix metalloproteinase inhibitors with improved bioavailability. J Med Chem45:5628-39 (2002) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Stromelysin-1
Name:Matrix metalloproteinase (2 and 3)
Synonyms:MMP-3 | Matrix metalloproteinase 3 | Matrix metalloproteinase-3 | Matrix metalloproteinase-3 (MMP-3) | Matrix metalloproteinase-3 (MMP3) | SL-1 | Stromelysin 1 | Transin-1
Type:Enzyme
Mol. Mass.:53973.13
Organism:Homo sapiens (Human)
Description: P08254
Residue:477
Sequence:
MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPV
VKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVN
YTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNV
LAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLY
HSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVS
TLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQF
WAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEP
GFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC
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  Blast E-value cutoff:
BDBM50056900
NameBDBM50056900
Synonyms:2-Carbamoylphenol | 2-Carboxamidophenol | 2-Hydroxybenzamide | CHEMBL27577 | OHB | Salicylic Acid amide | o-Hydroxybenzamide
TypeSmall organic molecule
Emp. Form.C7H7NO2
Mol. Mass.137.136
SMILESNC(=O)c1ccccc1O
Structure
n/a