Reaction Details Report a problem with these data
Target
Beta-galactosidase
Ligand
BDBM50133504
Substrate
n/a
Meas. Tech.
ChEMBL_37275 (CHEMBL656025)
Ki
46±n/a nM
Citation
 Ogawa, S; Fujieda, S; Sakata, Y; Ishizaki, M; Hisamatsu, S; Okazaki, K Synthesis and glycosidase inhibitory activity of some N-substituted 6-deoxy-5a-carba-beta-DL- and L-galactopyranosylamines. Bioorg Med Chem Lett 13:3461-3 (2003) [PubMed]  Article 
Target
Name:
Beta-galactosidase
Synonyms:
β-galactosidase | BGAL_BOVIN | Beta-galactosidase/Glucosylceramidase | GLB1
Type:
Protein
Mol. Mass.:
73420.88
Organism:
Bos taurus (Bovine)
Description:
n/a
Residue:
653
Sequence:
MPGVVRLLALLLVPLLLGSARGLHNATQRTFQIDYRRNRFLKDGQPFRYISGSIHYFRVPRFYWKDRLLKMKMAGLNAIQTYVAWNFHELQPGRYNFSGDHDVEHFIQLAHELGLLVILRPGPYICAEWDMGGLPAWLLEKKSIVLRSSDPDYLAAVDKWLGVLLPKMRPLLYKNGGPIITVQVENEYGSYLSCDYDYLRFLQKRFHDHLGEDVLLFTTDGVNERLLQCGALQGLYATVDFSPGTNLTAAFMLQRKFEPTGPLVNSEFYTGWLDHWGQRHSTVSSKAVAFTLHDMLALGANVNMYMFIGGTNFAYWNGANIPYQPQPTSYDYDAPLSEAGDLTEKYFALRDIIQKFAKVPEGPIPPSTPKFAYGKVALNKLKTVEDALNILCPSGPIKSVYPLTFIDVKQYFGFVLYRTMLPEDCSDPTPLSSPLSGVHDRAYVSVNGVAQGILERESVITLNITGKAGATLDLLVENMGRVNYGSSINDFKGLVSNLTLGSKILTNWEIFPLDMEDAVRSHLGTWGGRDRGYHNKARAHSPPTYALPTFYVGNFTIPSGIADLPQDTFIQFPGWTKGQVWINGFNLGRYWPVRGPQMTLFVPQHILVTSTPNTIVVLELEHAPCQDGGPELCTVEFVDKPVFRTVQTHRHAN
  
Inhibitor
Name:
BDBM50133504
Synonyms:
4-Methyl-6-(4-phenyl-butylamino)-cyclohexane-1,2,3-triol | CHEMBL324840
Type:
Small organic molecule
Emp. Form.:
C17H27NO3
Mol. Mass.:
293.4012
SMILES:
CC1CC(NCCCCc2ccccc2)C(O)C(O)C1O
Structure:
Search PDB for entries with ligand similarity: