Target
Fibroblast growth factor 1
Ligand
BDBM50144521
Substrate
n/a
Meas. Tech.
ChEBML_70464
Kd
32600±n/a nM
Citation
 Liu, LPing Li, CCochran, SFerro, V Application of the four-component Ugi condensation for the preparation of sulfated glycoconjugate libraries. Bioorg Med Chem Lett 14:2221-6 (2004) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 1
Synonyms:
Acidic fibroblast growth factor | Beta-endothelial cell growth factor | ECGF-beta | FGF1 | FGF1_HUMAN | FGFA | Fibroblast growth factor 1 (FGF-1) | HBGF-1 | Heparin-binding growth factor 1 | aFGF
Type:
Protein
Mol. Mass.:
17461.01
Organism:
Homo sapiens (Human)
Description:
P05230
Residue:
155
Sequence:
MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
  
Inhibitor
Name:
BDBM50144521
Synonyms:
CHEMBL3215303 | Sodium sulfated glycoconjugate derivative
Type:
Small organic molecule
Emp. Form.:
C40H62N4Na6O34S6
Mol. Mass.:
1473.255
SMILES:
[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CO[C@H]1O[C@@H](COCC(=O)N(CC(=O)NC2CCCCC2)[C@H]2CC[C@@H](CC2)N(CC(=O)NC2CCCCC2)C(=O)COC[C@@H]2O[C@H](OC)[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O |r,wU:27.21,10.4,8.1,72.70,60.57,84.83,wD:30.28,78.76,49.45,51.48,54.51,66.64,(18.06,,;19.93,,;,-13.82,;1.87,-13.82,;3.74,-13.82,;,-16.9,;.83,7.89,;-.17,9.05,;-1.69,8.76,;-2.19,7.31,;-3.7,7.02,;-4.21,5.56,;-3.2,4.4,;-3.7,2.94,;-2.69,1.78,;-1.18,2.07,;-3.2,.32,;-4.71,.03,;-5.72,1.2,;-5.21,2.65,;-7.23,.9,;-8.24,2.07,;-9.75,1.78,;-10.76,2.94,;-10.26,4.4,;-8.74,4.69,;-7.74,3.52,;-2.19,-.84,;-.68,-.55,;.33,-1.72,;-.17,-3.17,;-1.69,-3.46,;-2.69,-2.3,;.83,-4.33,;.33,-5.79,;-1.18,-6.08,;-2.19,-4.92,;-1.69,-7.54,;-3.2,-7.83,;-3.7,-9.28,;-5.21,-9.57,;-6.22,-8.41,;-5.72,-6.95,;-4.21,-6.66,;2.35,-4.04,;2.85,-2.59,;3.35,-5.21,;4.87,-4.92,;5.87,-6.08,;7.39,-5.79,;7.89,-4.33,;9.4,-4.04,;9.91,-2.59,;8.9,-1.42,;10.41,-5.21,;11.92,-4.92,;12.43,-3.46,;10.97,-2.96,;12.93,-2.01,;13.88,-3.97,;9.91,-6.66,;10.92,-7.83,;10.41,-9.28,;11.87,-9.79,;8.96,-8.78,;9.91,-10.74,;8.4,-6.95,;7.89,-8.41,;6.38,-8.7,;4.87,-8.99,;6.09,-7.19,;6.67,-10.21,;-4.71,8.18,;-6.22,7.89,;-6.73,6.43,;-7.23,4.98,;-8.18,6.94,;-5.27,5.93,;-4.21,9.64,;-5.21,10.8,;-6.73,10.51,;-6.44,9,;-7.02,12.02,;-8.24,10.22,;-2.69,9.93,;-2.19,11.38,;-3.2,12.55,;-2.03,13.55,;-4.36,11.54,;-4.21,13.71,)|
Structure:
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