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Target
Adenosine receptor A1
Ligand
BDBM50090697
Substrate
n/a
Meas. Tech.
ChEMBL_29112 (CHEMBL638724)
Ki
0.15±n/a nM
Citation
 Ferrarini, PL; Betti, L; Cavallini, T; Giannaccini, G; Lucacchini, A; Manera, C; Martinelli, A; Ortore, G; Saccomanni, G; Tuccinardi, T Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives. J Med Chem 47:3019-31 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50090697
Synonyms:
7-Chloro-2-phenyl-[1,8]naphthyridin-4-ol | 7-chloro-2-phenyl-1,8-naphthyridin-4-ol | CHEMBL97760
Type:
Small organic molecule
Emp. Form.:
C14H9ClN2O
Mol. Mass.:
256.687
SMILES:
Oc1cc(nc2nc(Cl)ccc12)-c1ccccc1
Structure:
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