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Target
Adenosine receptor A1
Ligand
BDBM50151203
Substrate
n/a
Meas. Tech.
ChEMBL_303307 (CHEMBL840033)
Ki
>500±n/a nM
Citation
 Vu, CB; Peng, B; Kumaravel, G; Smits, G; Jin, X; Phadke, D; Engber, T; Huang, C; Reilly, J; Tam, S; Grant, D; Hetu, G; Chen, L; Zhang, J; Petter, RC Piperazine derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists. J Med Chem 47:4291-9 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50151203
Synonyms:
2-Furan-2-yl-5-(4-phenethyl-piperazin-1-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ylamine | CHEMBL186725
Type:
Small organic molecule
Emp. Form.:
C20H22N8O
Mol. Mass.:
390.4417
SMILES:
Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN(CCc2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: