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Target
Alpha-1D adrenergic receptor
Ligand
BDBM50156303
Substrate
n/a
Meas. Tech.
ChEMBL_353200 (CHEMBL865721)
EC50
670±n/a nM
Citation
 Boschi, D; Tron, GC; Lazzarato, L; Chegaev, K; Cena, C; Di Stilo, A; Giorgis, M; Bertinaria, M; Fruttero, R; Gasco, A NO-donor phenols: a new class of products endowed with antioxidant and vasodilator properties. J Med Chem 49:2886-97 (2006) [PubMed]  Article 
Target
Name:
Alpha-1D adrenergic receptor
Synonyms:
ADA1D_RAT | Adra1a | Adra1d | Alpha adrenergic receptor 1A and 1D | Alpha-1D adrenergic receptor | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1
Type:
Protein
Mol. Mass.:
59375.97
Organism:
Rattus norvegicus (Rat)
Description:
P23944
Residue:
561
Sequence:
MTFRDILSVTFEGPRSSSSTGGSGAGGGAGTVGPEGGAVGGVPGATGGGAVVGTGSGEDNQSSTGEPGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRIHCRGAATSAKGYPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRLWAVYGHHWRASTGDARSDCAPSPRIAPPGAPLALTAHPGAGSADTPETQDSVSSSRKPASALREWRLLGPLQRPTTQLRAKVSSLSHKIRSGARRAETACALRSEVEAVSLNVPQDGAEAVICQAYEPGDYSNLRETDI
  
Inhibitor
Name:
BDBM50156303
Synonyms:
2-(3-benzenesulfonylfuroxan-4-yloxymethyl)-2,5,7,8-tetramethylchroman-6-ol | 2-(4-Benzenesulfonyl-5-oxy-furazan-3-yloxymethyl)-2,5,7,8-tetramethyl-chroman-6-ol | CHEMBL360593
Type:
Small organic molecule
Emp. Form.:
C22H24N2O7S
Mol. Mass.:
460.5
SMILES:
Cc1c(C)c2OC(C)(COc3no[n+]([O-])c3S(=O)(=O)c3ccccc3)CCc2c(C)c1O
Structure:
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