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Target
Aldehyde dehydrogenase 1, mitochondrial
Ligand
BDBM50250901
Substrate
n/a
Meas. Tech.
ChEMBL_509471 (CHEMBL1008107)
IC50
430000±n/a nM
Citation
 Kawagishi, H; Miyazawa, T; Kume, H; Arimoto, Y; Inakuma, T Aldehyde dehydrogenase inhibitors from the mushroom Clitocybe clavipes. J Nat Prod 65:1712-4 (2002) [PubMed]  Article 
Target
Name:
Aldehyde dehydrogenase 1, mitochondrial
Synonyms:
ALD1 | ALDH | ALDH1 | ALDHX_YEASX
Type:
PROTEIN
Mol. Mass.:
59519.82
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_509471
Residue:
533
Sequence:
MLATRNLVPIIRASIKWRIKLSALHYCMSDAETSEALLEDNSAYINNEKHNLFLEKIFSDYQPFKHDNRTQVSCSQHMRDYRPLLTLSSATRSVLFSLLASDMSIILSISPNTGILLCIGHLLASDIEDVVIVLSRGSPLVDLASTRIFKLAQNGTLRFAIKRTTFQELRFLRKSKDENVMEAATRGIITIRQLYYENKVLPLRFTGNVATHIEENLEFEEQITWRTHVDSSIFPNTRCAYPSGYGPSAKIPCLSHKPNDILAYTGSTLVGRVVSKLAPEQVMKKVTLESGGKSTMAVFIQHDVTWAVENTQFGVFDRQGQCCIAQSGYTVHRSTLSQIVENNLEKDPSYVLHVDTESDIRGPFILKIHFESIPRRINSAKAENSKVLCGGPRENSVYLYPTLSATLTDECRIMKEEVFAPIITILCVKTVDEAIQRGNNSKFGLAAYVTKENVHGIILSTALKTVKLFIICVHLASYQIPFGGNKNSGMGAELGKRALENYTEGNHVLPVSLVKETLAPNTETASPARWPIH
  
Inhibitor
Name:
BDBM50250901
Synonyms:
(E)-ethyl 8-oxooctadec-9-enoate | CHEMBL465239
Type:
Small organic molecule
Emp. Form.:
C20H36O3
Mol. Mass.:
324.498
SMILES:
CCCCCCCCC=CC(=O)CCCCCCC(=O)OCC |w:8.7|
Structure:
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