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Target
Beta-lactamase
Ligand
BDBM50049708
Substrate
n/a
Meas. Tech.
ChEMBL_553112 (CHEMBL966142)
Ki
60±n/a nM
Citation
 Power, P; Di Conza, J; Rodríguez, MM; Ghiglione, B; Ayala, JA; Casellas, JM; Radice, M; Gutkind, G Biochemical characterization of PER-2 and genetic environment of blaPER-2. Antimicrob Agents Chemother 51:2359-65 (2007) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
PER-2 beta-lactamase
Type:
PROTEIN
Mol. Mass.:
33451.67
Organism:
Citrobacter freundii
Description:
ChEMBL_553112
Residue:
308
Sequence:
MNVITKCVFTASALLMLGLSSFVVSAQSPLLKEQIETIVTGKKATVGVAVWGPDDLEPLLLNPFEKFPMQSVFKLHLAMLVLHQVDQGKLDLNQSVTVNRAAVLQNTWSPMMKDHQGDEFTVAVQQLLQYSVSHSDNVACDLLFELVGGPQALHAYIQSLGVKEAAVVANEAQMHADDQVQYQNWTSMKAAAQVLQKFEQKKQLSETSQALLWKWMVETTTGPQRLKGLLPAGTIVAHKTGTSGVRAGKTAATNDAGVIMLPDGRPLLVAVFVKDSAESERTNEAIIAQVAQAAYQFELKKLSAVSPD
  
Inhibitor
Name:
BDBM50049708
Synonyms:
CHEMBL148 | IMIPENEM
Type:
Small organic molecule
Emp. Form.:
C12H17N3O4S
Mol. Mass.:
299.346
SMILES:
C[C@@H](O)[C@@H]1[C@H]2CC(SCCN=CN)=C(N2C1=O)C(O)=O |r,w:11.11,c:12|
Structure:
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