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Target
Carbonic anhydrase 1
Ligand
BDBM50219498
Substrate
n/a
Meas. Tech.
ChEMBL_497169 (CHEMBL1002069)
IC50
420000±n/a nM
Citation
 Bayram, E; Senturk, M; Kufrevioglu, OI; Supuran, CT In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II. Bioorg Med Chem 16:9101-5 (2008) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 1
Synonyms:
CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA
Type:
Enzyme
Mol. Mass.:
28873.37
Organism:
Homo sapiens (Human)
Description:
P00915
Residue:
261
Sequence:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF
  
Inhibitor
Name:
BDBM50219498
Synonyms:
2-hydroxy-5-sulfo-benzoic acid | 5-Sulfosalicylic acid | CHEMBL229241 | MECLOCYCLINE SULFOSALICYLATE
Type:
Small organic molecule
Emp. Form.:
C7H6O6S
Mol. Mass.:
218.184
SMILES:
OC(=O)c1cc(ccc1O)S(O)(=O)=O
Structure:
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