Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 1
Ligand
BDBM50099736
Substrate
n/a
Meas. Tech.
ChEMBL_565116 (CHEMBL965760)
IC50
820±n/a nM
Citation
 Cao, S; Murphy, BT; Foster, C; Lazo, JS; Kingston, DG Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. Bioorg Med Chem 17:2276-81 (2009) [PubMed]  Article 
Target
Name:
Dual specificity protein phosphatase 1
Synonyms:
3ch134 | DUS1_MOUSE | Dusp1 | Mkp1 | Ptpn10 | Ptpn16
Type:
PROTEIN
Mol. Mass.:
39372.46
Organism:
Mus musculus
Description:
ChEMBL_565116
Residue:
367
Sequence:
MVMEVGILDAGGLRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSASLDGAKRDGTLALAAGALCREARSTQVFFLQGGYEAFSASCPELCSKQSTPTGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLKSPITTSPSC
  
Inhibitor
Name:
BDBM50099736
Synonyms:
4-Ethoxy-[1,2]naphthoquinone | 4-ethoxynaphthalene-1,2-dione | CHEMBL50620
Type:
Small organic molecule
Emp. Form.:
C12H10O3
Mol. Mass.:
202.206
SMILES:
CCOC1=CC(=O)C(=O)c2ccccc12 |t:3|
Structure:
Search PDB for entries with ligand similarity: