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Target
3-dehydroquinate synthase
Ligand
BDBM50028883
Substrate
n/a
Meas. Tech.
ChEMBL_358 (CHEMBL615413)
KON
1000 M-1s-1
Citation
 Montchamp, JL; Piehler, LT; Tolbert, TJ; Front, JW The basis for slowly reversible inhibition of dehydroquinate synthase: a case of mistaken identity? Bioorg Med Chem Lett 2:1349-1352 (1992)    Article 
Target
Name:
3-dehydroquinate synthase
Synonyms:
AROB_ECOLI | aroB
Type:
Enzyme
Mol. Mass.:
38878.02
Organism:
Escherichia coli (strain K12)
Description:
P07639
Residue:
362
Sequence:
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLKRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
  
Inhibitor
Name:
BDBM50028883
Synonyms:
(1S,3S,5R)-1,3-Dihydroxy-5-phosphonomethyl-cyclohexanecarboxylic acid | CHEMBL178075
Type:
Small organic molecule
Emp. Form.:
C8H15O7P
Mol. Mass.:
254.1743
SMILES:
O[C@H]1C[C@@H](CP(O)(O)=O)C[C@](O)(C1)C(O)=O
Structure:
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