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Target
D(2) dopamine receptor
Ligand
BDBM50280816
Substrate
n/a
Meas. Tech.
ChEBML_61112
IC50
>100±n/a nM
Citation
 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C New indole derivatives as potent and selective serotonin uptake inhibitors Bioorg Med Chem Lett 3:1913-1918 (1993)    Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2_MOUSE | Dopamine D2 receptor | Dopamine Receptor D2 | Drd2
Type:
Enzyme
Mol. Mass.:
50957.64
Organism:
Mus musculus (Mouse)
Description:
P61168
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50280816
Synonyms:
CHEMBL293729 | N-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-N-methyl-benzenesulfonamide
Type:
Small organic molecule
Emp. Form.:
C23H28FN3O2S
Mol. Mass.:
429.551
SMILES:
CN(CCN1CCC(Cc2c[nH]c3ccc(F)cc23)CC1)S(=O)(=O)c1ccccc1
Structure:
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