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Target
S-ribosylhomocysteine lyase
Ligand
BDBM50304167
Substrate
n/a
Meas. Tech.
ChEMBL_601072 (CHEMBL1071831)
Ki
8800±n/a nM
Citation
 Wnuk, SF; Robert, J; Sobczak, AJ; Meyers, BP; Malladi, VL; Zhu, J; Gopishetty, B; Pei, D Inhibition of S-ribosylhomocysteinase (LuxS) by substrate analogues modified at the ribosyl C-3 position. Bioorg Med Chem 17:6699-706 (2009) [PubMed]  Article 
Target
Name:
S-ribosylhomocysteine lyase
Synonyms:
LUXS_BACSU | luxS | ytjB
Type:
PROTEIN
Mol. Mass.:
17709.00
Organism:
Bacillus subtilis
Description:
ChEMBL_764478
Residue:
157
Sequence:
MPSVESFELDHNAVVAPYVRHCGVHKVGTDGVVNKFDIRFCQPNKQAMKPDTIHTLEHLLAFTIRSHAEKYDHFDIIDISPMGCQTGYYLVVSGEPTSAEIVDLLEDTMKEAVEITEIPAANEKQCGQAKLHDLEGAKRLMRFWLSQDKEELLKVFG
  
Inhibitor
Name:
BDBM50304167
Synonyms:
CHEMBL610483 | S-(3,5-Dideoxy-3-fluoro-1-O-methyl-D-xylofuranos-5-yl)-L-homocysteine
Type:
Small organic molecule
Emp. Form.:
C10H18FNO5S
Mol. Mass.:
283.317
SMILES:
COC1O[C@H](CSCC[C@H](N)C(O)=O)[C@H](F)[C@H]1O |r|
Structure:
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