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Target
Lysophosphatidic acid receptor 2
Ligand
BDBM50271701
Substrate
n/a
Meas. Tech.
ChEMBL_605120 (CHEMBL1073934)
IC50
355±n/a nM
Citation
 Fells, JI; Tsukahara, R; Liu, J; Tigyi, G; Parrill, AL Structure-based drug design identifies novel LPA3 antagonists. Bioorg Med Chem 17:7457-64 (2009) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 2
Synonyms:
EDG4 | LPA receptor 2 | LPA-2 | LPA2 | LPAR2 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 | Lysophosphatidic acid receptor Edg-4
Type:
PROTEIN
Mol. Mass.:
39103.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1451385
Residue:
351
Sequence:
MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
  
Inhibitor
Name:
BDBM50271701
Synonyms:
2,6-bis(3-carboxyacrylamido)benzoic acid | 4,4'-(2-carboxy-1,3-phenylene)bis(azanediyl)bis(4-oxobut-2-enoic acid) | CHEMBL485119
Type:
Small organic molecule
Emp. Form.:
C15H12N2O8
Mol. Mass.:
348.2644
SMILES:
OC(=O)\C=C\C(=O)Nc1cccc(NC(=O)\C=C\C(O)=O)c1C(O)=O
Structure:
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