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Target6-phospho-1-fructokinase
LigandBDBM50320386
Substrate/Competitorn/a
Meas. Tech.ChEMBL_634086
IC50 170000±n/a nM
Citation Ngantchou, INyasse, BDenier, CBlonski, CHannaert, VSchneider, B Antitrypanosomal alkaloids from Polyalthia suaveolens (Annonaceae): their effects on three selected glycolytic enzymes of Trypanosoma brucei. Bioorg Med Chem Lett20:3495-8 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
6-phospho-1-fructokinase
Name:6-phospho-1-fructokinase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:53537.94
Organism:Trypanosoma brucei
Description:ChEMBL_1288121
Residue:487
Sequence:
MAVESRSRVTSKLVKAHRAMLNSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIM
YNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSIT
LTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKE
MVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFG
FQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPI
SEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGRGSGGYDASGNKKLIDIGVILTEKVKAF
LKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHN
NYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRL
HEELAKL
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  Blast E-value cutoff:
BDBM50320386
NameBDBM50320386
Synonyms:3-O-acetylgreenwayodendrin | CHEMBL1083629
TypeSmall organic molecule
Emp. Form.C25H33NO2
Mol. Mass.379.535
SMILESCC(=O)O[C@H]1CC[C@]2(C)[C@H]3Cc4cc5ccccc5n4[C@]3(C)CC[C@H]2C1(C)C |r|
Structure
n/a