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Target6-phospho-1-fructokinase
LigandBDBM50320387
Substrate/Competitorn/a
Meas. Tech.ChEMBL_634086
IC50 30000±n/a nM
Citation Ngantchou, INyasse, BDenier, CBlonski, CHannaert, VSchneider, B Antitrypanosomal alkaloids from Polyalthia suaveolens (Annonaceae): their effects on three selected glycolytic enzymes of Trypanosoma brucei. Bioorg Med Chem Lett20:3495-8 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
6-phospho-1-fructokinase
Name:6-phospho-1-fructokinase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:53537.94
Organism:Trypanosoma brucei
Description:ChEMBL_1288121
Residue:487
Sequence:
MAVESRSRVTSKLVKAHRAMLNSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIM
YNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSIT
LTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKE
MVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFG
FQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPI
SEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGRGSGGYDASGNKKLIDIGVILTEKVKAF
LKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHN
NYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRL
HEELAKL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50320387
NameBDBM50320387
Synonyms:CHEMBL1086376 | polyveoline
TypeSmall organic molecule
Emp. Form.C23H33NO
Mol. Mass.339.5142
SMILESC[C@@]12CC[C@H]3C(C)(C)[C@H](O)CC[C@]3(C)[C@@H]1C[C@@H]1Nc3ccccc3[C@H]21 |r|
Structure
n/a