Reaction Details Report a problem with these data
Target
Fructose-bisphosphate aldolase A
Ligand
BDBM50320387
Substrate
n/a
Meas. Tech.
ChEMBL_634088 (CHEMBL1118360)
IC50
270000±n/a nM
Citation
 Ngantchou, I; Nyasse, B; Denier, C; Blonski, C; Hannaert, V; Schneider, B Antitrypanosomal alkaloids from Polyalthia suaveolens (Annonaceae): their effects on three selected glycolytic enzymes of Trypanosoma brucei. Bioorg Med Chem Lett 20:3495-8 (2010) [PubMed]  Article 
Target
Name:
Fructose-bisphosphate aldolase A
Synonyms:
ALDOA | ALDOA_RABIT
Type:
PROTEIN
Mol. Mass.:
39351.00
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_813854
Residue:
364
Sequence:
MPHSHPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFISNHAY
  
Inhibitor
Name:
BDBM50320387
Synonyms:
CHEMBL1086376 | polyveoline
Type:
Small organic molecule
Emp. Form.:
C23H33NO
Mol. Mass.:
339.5142
SMILES:
C[C@@]12CC[C@H]3C(C)(C)[C@H](O)CC[C@]3(C)[C@@H]1C[C@@H]1Nc3ccccc3[C@H]21 |r|
Structure:
Search PDB for entries with ligand similarity: