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TargetMultidrug resistance protein mdtK
LigandBDBM50336500
Substrate/Competitorn/a
Meas. Tech.ChEMBL_720698
Kd 3000±n/a nM
Citation Long, FRouquette-Loughlin, CShafer, WMYu, EW Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. Antimicrob Agents Chemother52:3052-60 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Multidrug resistance protein mdtK
Name:Multidrug resistance protein mdtK
Synonyms:Multidrug-efflux transporter
Type:PROTEIN
Mol. Mass.:49460.10
Organism:Escherichia coli (strain K12)
Description:ChEMBL_720698
Residue:457
Sequence:
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILF
GHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENID
PALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIY
GHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQ
LGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVG
YRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLL
AAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAG
FWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR
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BDBM50336500
NameBDBM50336500
Synonyms:(E)-N-(9-(2-(ethoxycarbonyl)phenyl)-6-(ethylamino)-2,7-dimethyl-3H-xanthen-3-ylidene)ethanaminium chloride | CHEMBL402140 | [9-(2-ethoxycarbonyl-phenyl)-6-ethylamino-2,7-dimethyl-xanthen-(3E)-ylidene]-ethyl-ammonium; chloride | rhodamine 6G
TypeSmall organic molecule
Emp. Form.C28H30N2O3
Mol. Mass.442.5494
SMILESCCNc1cc2oc3c\c(=N/CC)c(C)cc3c(-c3ccccc3C(=O)OCC)c2cc1C |(-6.01,-19.07,;-4.68,-18.3,;-3.35,-19.07,;-2.01,-18.31,;-.68,-19.08,;.65,-18.3,;1.98,-19.07,;3.32,-18.3,;4.65,-19.07,;5.99,-18.3,;7.32,-19.07,;7.32,-20.61,;8.66,-21.38,;5.98,-16.75,;7.31,-15.98,;4.65,-15.99,;3.33,-16.76,;1.99,-15.98,;1.99,-14.45,;.66,-13.68,;.65,-12.15,;1.99,-11.37,;3.33,-12.14,;3.33,-13.68,;4.66,-14.45,;4.2,-15.5,;6.2,-14.46,;6.98,-13.13,;8.52,-13.14,;.65,-16.75,;-.68,-15.99,;-2.01,-16.76,;-3.34,-15.99,)|
Structure
n/a