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TargetL-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase
LigandBDBM50339905
Substrate/Competitorn/a
Meas. Tech.ChEMBL_740791
Kd 48.5±n/a nM
Citation Gutierrez-Lugo, MTBewley, CA Susceptibility and mode of binding of the Mycobacterium tuberculosis cysteinyl transferase mycothiol ligase to tRNA synthetase inhibitors. Bioorg Med Chem Lett21:2480-3 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase
Name:L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase
Synonyms:L-Cys:GlcN-Ins ligase | MSH ligase | Mycothiol ligase
Type:PROTEIN
Mol. Mass.:45583.42
Organism:Mycobacterium tuberculosis
Description:ChEMBL_754210
Residue:414
Sequence:
MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV
TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV
LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR
DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR
IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV
LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV
VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50339905
NameBDBM50339905
Synonyms:5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE | 5'-O-[N-(L-cysteinyl)sulfamoyl]adenosine | CHEMBL1163074 | CysSA
TypeSmall organic molecule
Emp. Form.C13H19N7O7S2
Mol. Mass.449.463
SMILESN[C@@H](CS)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Structure
n/a