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Target
6-phosphogluconate dehydrogenase, decarboxylating
Ligand
BDBM50148769
Substrate
n/a
Meas. Tech.
ChEMBL_744988 (CHEMBL1772003)
Ki
1520±n/a nM
Citation
 Yep, A; Sorenson, RJ; Wilson, MR; Showalter, HD; Larsen, SD; Keller, PR; Woodard, RW Enediol mimics as inhibitors of the D-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis. Bioorg Med Chem Lett 21:2679-82 (2011) [PubMed]  Article 
Target
Name:
6-phosphogluconate dehydrogenase, decarboxylating
Synonyms:
6-phosphogluconate dehydrogenase, decarboxylating, putative
Type:
PROTEIN
Mol. Mass.:
52169.87
Organism:
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Description:
ChEMBL_744988
Residue:
479
Sequence:
MSMDVGVVGLGVMGANLALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAGAATDSTIEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ
  
Inhibitor
Name:
BDBM50148769
Synonyms:
(R)-Phosphoric acid mono-((R)-3-carbamoyl-2,3-dihydroxy-propyl) ester | CHEMBL323922
Type:
Small organic molecule
Emp. Form.:
C4H10NO7P
Mol. Mass.:
215.0985
SMILES:
NC(=O)[C@H](O)[C@H](O)COP(O)(O)=O
Structure:
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